Ass.-Prof. Dr. Samuel Matthias Meier-Menches, Privatdoz. BSc MSc
Summer term 2022
270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry
Winter term 2021
270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry







Babak, M. V., Chong, K. R., Rapta, P., Zannikou, M., Tang, H. M., Reichert, L., Chang, M. R., Kushnarev, V., Heffeter, P., Meier-Menches, S. M., Lim, Z. C., Yap, J. Y., Casini, A., Balyasnikova, I. V., & Ang, W. H. (2021). Interfering with Metabolic Profile of Triple-Negative Breast Cancers Using Rationally Designed Metformin Prodrugs. Angewandte Chemie (International Edition), 60(24), 13405-13413. https://doi.org/10.1002/anie.202102266


Voloshin, Y. Z., Dudkin, S. V., Belova, S. A., Gherca, D., Samohvalov, D., Manta, C-M., Lungan, M-A., Meier-Menches, S. M., Rapta, P., Darvasiova, D., Malcek, M., Pombeiro, A. J. L., Martins, L. M. D. R. S., & Arion, V. B. (2021). Spectroelectrochemical Properties and Catalytic Activity in Cyclohexane Oxidation of the Hybrid Zr/Hf-Phthalocyaninate-Capped Nickel(II) and Iron(II) tris-Pyridineoximates and Their Precursors. Molecules, 26(2), [336]. https://doi.org/10.3390/molecules26020336


Losytskyy, M., Chornenka, N., Vakarov, S., Meier-Menches, S. M., Gerner, C., Potocki, S., Arion, V. B., Gumienna-Kontecka, E., Voloshin, Y., & Kovalska, V. (2020). Sensing of Proteins by ICD Response of Iron(II) Clathrochelates Functionalized by Carboxyalkylsulfide Groups. Biomolecules, 10(12), [1602]. https://doi.org/10.3390/biom10121602


Baier, D. S., Schönhacker-Alte, B., Pirker, C., Englinger, B., Mohr, T., Meier-Menches, S., Roehrl, C., Moser, P., Laemmerer, A., Neuditschko, B., Niederstaetter, L., Brunmair, J., Schaier, M., Regner, B., Nowikovsky, K., Gerner, C., Koellensperger, G., Heffeter, P., Keppler, B. K., & Berger, W. (2020). Lipid metabolism as target and modulator of KP1339 anticancer activity. Cancer Research, 80(16), [Meeting Abstract: 1839 ]. https://doi.org/10.1158/1538-7445.AM2020-1839




Englinger, B., Laemmerer, A., Moser, P., Kallus, S., Roehrl, C., Pirker, C., Baier, D., Mohr, T., Niederstaetter, L., Meier-Menches, S. M., Gerner, C., Gabler, L., Gojo, J., Timelthaler, G., Senkiv, J., Jaeger, W., Kowol, C. R., Heffeter, P., & Berger, W. (2020). Lipid droplet-mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib. International Journal of Cancer. https://doi.org/10.1002/ijc.32924

Kreutz, D., Gerner, C., & Meier-Menches, S. M. (2019). Enabling Methods to Elucidate the Effects of Metal-based Anticancer Agents. In A. Vessieres, S. M. Meier-Menches, & A. Casini (Eds.), Metal-based Anticancer Agents (pp. 246-270). Royal Society of Chemistry. RSC Metallobiology Vol. 2019-January No. 14 https://doi.org/10.1039/9781788016452-00246

Casini, A., Vessières, A., & Meier-Menches, S. M. (2019). Metal-based Anticancer Agents. Royal Society of Chemistry. Metallobiology

Determining Metabolic traits in the realm of chronic disease

Samuel Matthias Meier-Menches (Invited speaker)

12 Nov 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Enrichment of the selenoproteome

Lukas Skos (Speaker) & Samuel Matthias Meier-Menches (Contributor)

20 Oct 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Small molecule effects in complex systems

Samuel Matthias Meier-Menches (Invited speaker)

11 Oct 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification of linked metabolites allows a reliable and quantitative analysis of the finger sweat

Mathias Gotsmy (Speaker), Julia Brunmair (Contributor), Andrea Bileck (Contributor), Astrid Slany (Contributor), Samuel Matthias Meier-Menches (Contributor), Christopher Gerner (Contributor) & Jürgen Zanghellini (Contributor)

23 Sep 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Epithelial cell line derived from endometriotic lesion mimics macrophage nervous mechanism of pain generation on proteo-me and metabolome levels

Julia Brunmair (Speaker), Benjamin Neuditschko (Contributor), Marlene Leibetseder (Contributor), Gerhard Hagn (Contributor), Lukas Skos (Contributor), Marlene C. Gerner (Contributor), Samuel Matthias Meier-Menches (Contributor), Iveta Yotova (Contributor) & Christopher Gerner (Contributor)

7 Sep 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification of Metabolic Pairs Allow a Reliable and Quantitative Analysis of the Finger Sweat Metabolome

Mathias Gotsmy (Speaker), Samuel Matthias Meier-Menches (Contributor), Christopher Gerner (Contributor), Jürgen Zanghellini (Contributor), Julia Brunmair (Contributor), Andrea Bileck (Contributor) & Astrid Slany (Contributor)

25 Jul 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Finger Sweat Analysis Enables Metabolic Biomonitoring in Humans

Julia Brunmair (Speaker), Mathias Gotsmy (Contributor), Andrea Bileck (Contributor), Jürgen Zanghellini (Contributor), Samuel Matthias Meier-Menches (Contributor) & Christopher Gerner (Contributor)

22 Jun 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Reliable Quantitative Finger Sweat Metabolome Analysis

Mathias Gotsmy (Speaker), Julia Brunmair (Contributor), Andrea Bileck (Contributor), Astrid Slany (Contributor), Samuel Matthias Meier-Menches (Contributor), Christopher Gerner (Contributor) & Jürgen Zanghellini (Contributor)

23 Feb 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Analytical methods as connecting elements in translational research

Samuel Matthias Meier-Menches (Invited speaker)

13 Jan 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Mass Spectrometry for Elucidating Activation Mechanisms and Modes of Action of Anticancer Metallodrugs on the Molecular Level

Samuel Matthias Meier-Menches (Invited speaker)

10 Jul 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Mass Spectrometric Techniques to Study Reactive Metallodrugs on the Molecular Level

Samuel Matthias Meier-Menches (Invited speaker)

5 Mar 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Analytical Approaches to Connect the Chemical Reactivity of Small Molecules to their Biological Effects

Samuel Matthias Meier-Menches (Invited speaker)

20 Jan 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Elucidating Activation Mechanisms and Cellular Effects of Anticancer Metallodrugs on the Molecular Level

Samuel Matthias Meier-Menches (Invited speaker)

28 Nov 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Affinity-Mass Spectrometry to Determine Target Proteins of Reactive Small Molecules

Samuel Matthias Meier-Menches (Speaker)

30 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Affinity-Mass Spectrometry to Determine Target Proteins of Reactive Small Molecules

Samuel Matthias Meier-Menches (Speaker)

10 Mar 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Eicosanoids as underestimated molecular players relevant for tumor biology and mechanisms of metastasis

Lukas Janker (Invited speaker), Laura Niederstätter (Contributor), Benjamin Neuditschko (Contributor), Julia Brunmair (Contributor), Samuel Matthias Meier-Menches (Contributor) & Christopher Gerner (Contributor)

6 Dec 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Emerging Proteomics Methods to Elucidate Metallodrug Effects in the Cellular Context

Samuel Matthias Meier-Menches (Invited speaker)

24 Jun 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Targeting G-Quadruplex Nucleic Acid Structures with Caffeine Gold Compounds for Cancer Treatment

Samuel Matthias Meier-Menches (Invited speaker)

29 Nov 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Elucidating the Target Selectivity of Metal-based Anticancer Agents

Samuel Matthias Meier-Menches (Invited speaker)

25 Oct 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Aging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia

Rupert Laurenz Mayer (Speaker), Astrid Slany (Contributor), Andrea Bileck (Contributor), Johanna Mader (Contributor), Samuel Matthias Meier (Contributor), Tobias Pukrop (Contributor), Albrecht Reichle (Contributor), Josef D. Schwarzmeier (Contributor) & Christopher Gerner (Contributor)

6 Sep 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Multi-omics Analysis of Serum Samples Demonstrates Reprogramming of Organ Functions Via Systemic Calcium Mobilization and Platelet Activation in Metastatic Melanoma

Besnik Muqaku (Speaker), Martin Eisinger (Contributor), Samuel Matthias Meier (Contributor), Ammar Tahir (Contributor), Tobias Pukrop (Contributor), Sebastian Haferkamp (Contributor), Astrid Slany (Contributor), Albrecht Reichle (Contributor) & Christopher Gerner (Contributor)

6 Sep 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


On the molecular mechanism of action of organometallic anticancer drugs

Christopher Gerner (Speaker), Samuel Matthias Meier (Contributor), Dominique Kreutz (Contributor), Tamara Weiss (Contributor), Andrea Bileck (Contributor), Bernhard Keppler (Contributor) & Gerhard Wiche (Contributor)

14 Aug 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Unravelling the Reactivity of Gold ‐ based Metallodrugs with Zinc Finger Domains and G ‐ Quadruplex DNA by Mass Spectrometry

Samuel Matthias Meier-Menches (Speaker)

14 Aug 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Post-digestion stabilization of osmium enables quantitation by ICP-MS in cell culture and tissue

Matthias Klose (Speaker), Michaela Hejl (Contributor), Petra Heffeter (Contributor), Michael Jakupec (Contributor), Samuel Matthias Meier (Contributor), Walter Berger (Contributor) & Bernhard Keppler (Contributor)

17 May 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


DNA vs. Protein – Capillary Zone Electrophoresis–Mass Spectrometry to characterize Metallodrug binding Preferences

Christian Artner (Speaker), Hannah U. Holtkamp (Contributor), Christian G. Hartinger (Contributor), Samuel Matthias Meier (Contributor) & Bernhard Keppler (Contributor)

12 May 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Proteomics for Understanding Metallodrug Effects

Samuel Matthias Meier-Menches (Invited speaker), Dominique Kreutz (Contributor), Bernhard Keppler (Contributor) & Christopher Gerner (Contributor)

4 Dec 2016

Activity: Talks and presentationsTalk or oral contributionScience to Science


Proteomics for Understanding Metallodrug Effects

Samuel Matthias Meier-Menches (Speaker) & Christopher Gerner (Contributor)

5 Sep 2016

Activity: Talks and presentationsTalk or oral contributionScience to Science


Reproducible quantification of metabolites from fingertips via triple-quadrupole mass spectrometry

Samuel Matthias Meier (Speaker)

8 May 2016

Activity: Talks and presentationsTalk or oral contributionOther


Mass spectrometry based assays in preclinical metallodrug research

Samuel Matthias Meier (Invited speaker)

20 Nov 2014

Activity: Talks and presentationsTalk or oral contributionOther


The Structural Determinants for Cytotoxic Activity of a Ruthenium Arene Peptide Conjugate

Samuel Matthias Meier (Speaker)

8 Apr 2013

Activity: Talks and presentationsTalk or oral contributionOther


(Thio)pyronederived organometallics: an approach for new metalbased anticancer drugs

Samuel Matthias Meier (Contributor)

18 Jun 2012

Activity: Talks and presentationsTalk or oral contributionOther



Top-Down High Resolution Mass Spectrometry of Ubiquitin-Oxaliplatin Adducts

Samuel Matthias Meier (Speaker)

23 Feb 2011

Activity: Talks and presentationsTalk or oral contributionOther


Dissecting Temporal Metallodrug Effects in Cancer Cells

Samuel Matthias Meier-Menches (Speaker) & Christopher Gerner (Contributor)

30 Jun 2010

Activity: Talks and presentationsTalk or oral contributionScience to Science


Dissecting Temporal Metallodrug Effects in Cancer Cells

Samuel Matthias Meier-Menches (Speaker) & Christopher Gerner (Contributor)

30 Jun 2010

Activity: Talks and presentationsTalk or oral contributionScience to Science


Investigation of the Binding Interaction of Oxaliplatin to Ubiquitin by Mass Spectrometric Methods

Samuel Matthias Meier (Speaker)

29 Mar 2010

Activity: Talks and presentationsTalk or oral contributionOther


Affinity-Mass Spectrometry to Determine Target Proteins of Reactive Small Molecules

Samuel Matthias Meier-Menches (Speaker)

10 Mar 2010

Activity: Talks and presentationsTalk or oral contributionScience to Science


Department of Analytical Chemistry

Währinger Straße 38
1090 Wien

T: +43-1-4277-52373

samuel.meier@univie.ac.at