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Assoz. Prof. Dr. Samuel Meier-Menches

T: +43-1-4277-52373

samuel.meier-menches@univie.ac.at

meiermencheslab.univie.ac.at

Summer term 2026

270013 SE Writing of the Bachelor´s Thesis

270084 LP Basic course in analytical chemistry

270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry

270130 PR Practical Course Spectroscopy - UV/VIS, IR/Ra, NMR

270189 PR Metabolic Phenotyping

270297 VO Receptor Ligand Interactions

530017 SE Bioanalysis and Translational Research

Winter term 2025

270013 SE Writing of the Bachelor´s Thesis

270084 LP Basic course in analytical chemistry

270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry

270130 PR Practical Course Spectroscopy - UV/VIS, IR/Ra, NMR

270244 PR Mass Spectrometry I

270251 VU Evaluation Strategies of Big Data

Summer term 2025

270013 SE Writing of the Bachelor´s Thesis

270077 PR Basic Laboratory Course II A

270101 UE Practice in Analytical Chemistry

270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry

270189 PR Metabolic Phenotyping

270297 VO Receptor Ligand Interactions

950195 VO General and applied biochemistry

Fiduccia, I., Vitale, E., Varrica, R., Ricci, D., Marino, S., Zito, A., Pace, A., Colige, A., Moutschen, M., Borutzki, Y., Bileck, A., Meier-Menches, S. M., Lentini, L., & Pibiri, I. (2026). Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency. Molecular Therapy Nucleic Acids, 37(1), Article 102808. https://doi.org/10.1016/j.omtn.2025.102808

Bormio Nunes, J. H., Hacker, C., Caban, M., Valcanover, D., Yassemipour, P. A., Türck, S., Ott, I., Skos, L., Bileck, A., Gerner, C., Meier-Menches, S. M., Mohr, T., Berger, W., Kowol, C. R., & Heffeter, P. (2026). Structure-Activity Relationships of Silver(I)- and Gold(I)-NHC Complexes Reveal Distinctly Different Responses of Cisplatin-Resistant Ovarian Cancer to Bis-NHC-Gold(I) Derivatives. Journal of Medicinal Chemistry, Article PMID 9716531. Advance online publication. https://doi.org/10.1021/acs.jmedchem.5c02355

Thomas, S. R., Iellici, T., Park, M., Klaus, E., Bileck, A., Gerner, C., Meier-Menches, S. M., & Casini, A. (2026). A Gold-PROTAC Degrades the Oncogenic Tyrosine Kinase MERTK: Insights into the Degradome from a Steady-State System. ACS Chemical Biology, 21(1), 170-186. https://doi.org/10.1021/acschembio.5c00860

Rocha, M., Petsch, J., Schultheis, D., Zrelski, M. M., Fichtinger, P., Koneczny, I., Meier-Menches, S., Wiche, G., Schröder, R., & Winter, L. (2025). Consequences of plectin ablation on the various intermediate filament systems in skeletal muscle. European Journal of Cell Biology, 104(4), Article 151522. https://doi.org/10.1016/j.ejcb.2025.151522

Karasová, M., Jobst, M., Framke, D., Bergen, J., Meier-Menches, S., Keppler, B., Koellensperger, G., Zanghellini, J., Gerner, C., & Del Favero, G. (2025). Mechanical cues rewire lipid metabolism and support chemoresistance in epithelial ovarian cancer cell lines OVCAR3 and SKOV3. Cell communication and signaling, 23(1), Article 193. https://doi.org/10.1186/s12964-025-02144-9

Outla, Z., Kosla, J., Prechova, M., Frick, L., Janker-Bortel, P., Borutzki, Y., Bileck, A., Gerner, C., Meier-Menches, S. M., Osmanagic-Myers, S., & Gregor, M. (2025). Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin. Molecular Oncology. Advance online publication. https://doi.org/10.1002/1878-0261.70186

Wolf, M., Wasinger, D., Donhauser, V., Moliterno, P., Keppler, B. K., Gerner, C., Widhalm, K., & Meier-Menches, S. M. (2025). Eccrine sweat reveals normalization of artificial sweetener levels in children with overweight after nutritional education. Iscience, 28(11), Article 113736. https://doi.org/10.1016/j.isci.2025.113736

Jobst, M., Crudo, F., Marko, D., Bileck, A., Meier-Menches, S. M., Gerner, C., & Del Favero, G. (2025). Retrograde rearrangement of mitochondria correlates with nuclear deformation and genotoxic damage. Iscience, 28(8), Article 112955. https://doi.org/10.1016/j.isci.2025.112955

Rosner, A., Skos, L., Mendrina, T., Baier-Romfeld, D., Hejl, M., Borutzki, Y., Gradl, M., Geisler, H., Mohr, T., Legin, A., Jakupec, M. A., Bileck, A., Gerner, C., Koellensperger, G., Heffeter, P., Berger, W., Keppler, B. K., Kandioller, W., & Meier-Menches, S. M. (2025). Selectivity for TP53 signalling drives the mode of action of a highly potent N,O,O-tridentate naphthoquinone-based organo-ruthenium anticancer drug candidate. Chemical Science. Advance online publication. https://doi.org/10.1039/d5sc00735f

Schmidl, D., Pai, V., Bileck, A., Hommer, N., Janku, P., Lindner, T., Kauer, V., Rumpf, B., Haslacher, H., Hagn, G., Meier-Menches, S. M., Schmetterer, L., Gerner, C., & Garhöfer, G. (2025). Retinal microcirculation in patients that have recovered from acute COVID-19 infection. Journal of Vascular Research, 62(SUPPL 1), Article Meeting Abstract 90.

Outla, Z., Oyman-Eyrilmez, G., Korelova, K., Prechova, M., Frick, L., Sarnova, L., Bisht, P., Novotna, P., Kosla, J., Janker-Bortel, P., Borutzki, Y., Bileck, A., Gerner, C., Rahbari, M., Rahbari, N., Birgin, E., Kvasnicova, B., Galisova, A., Sulkova, K., ... Gregor, M. (2025). Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis. eLife, 13. https://doi.org/10.7554/eLife.102205

Bolliger, M., Wasinger, D., Brunmair, J., Hagn, G., Wolf, M., Preindl, K., Reiter, B., Bileck, A., Gerner, C., Fitzal, F., & Meier-Menches, S. M. (2025). Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria. The EPMA journal, 16(1), 165-182. https://doi.org/10.1007/s13167-025-00396-6

Zott, T., Wolf, M., Plessl-Walder, G., Regele, H., Bergmann, M., Meier-Menches, S. M., Gerner, C., Silberhumer, G. R., & Bileck, A. (2025). Proteomic Analysis of FFPE Tissue Samples Identifies Potential Molecular Mechanisms Mediating Resistance to Radiotherapy in Rectal Cancer. Journal of Proteome Research. Advance online publication. https://doi.org/10.1021/acs.jproteome.5c00114

Hagn, G., Meier-Menches, S. M., Plessl-Walder, G., Mitra, G., Mohr, T., Preindl, K., Schlatter, A., Schmidl, D., Gerner, C., Garhöfer, G., & Bileck, A. (2024). Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets. Journal of Proteome Research, 23(8), 3064-3075. https://doi.org/10.1021/acs.jproteome.3c00761

Gerner, I., Meier-Menches, S. M., Bileck, A., Gueltekin, S., Gerner, C., & Jenner, F. (2024). Metabolic Profiling Of Tendon And Cartilage Healing. Tissue engineering. Part A, 30(15-16), S6-S7.

Skos, L., Schmidt, C., Thomas, S. R., Park, M., Geiger, V., Wenisch, D., Bonsignore, R., Del Favero, G., Mohr, T., Bileck, A., Gerner, C., Casini, A., & Meier-Menches, S. M. (2024). Gold-templated covalent targeting of the CysSec-dyad of thioredoxin reductase 1 in cancer cells. Cell Reports Physical Science, 5(7), Article 102072. https://doi.org/10.1016/j.xcrp.2024.102072

Janker-Bortel, P., Hagn, G., Skos, L., Bileck, A., Paulitschke, V., Paulitschke, P., Gleiter, L., Mohr, T., Gerner, C., & Meier-Menches, S. M. (2024). Memory effects of prior subculture may impact the quality of multiomic perturbation profiles. Proceedings of the National Academy of Sciences of the United States of America, 121(29), Article e2313851121. https://doi.org/10.1073/pnas.2313851121

Pai, V., Bileck, A., Hommer, N., Janku, P., Lindner, T., Kauer, V., Rumpf, B., Haslacher, H., Hagn, G., Meier-Menches, S. M., Schmetterer, L., Schmidl, D., Gerner, C., & Garhöfer, G. (2024). Impaired retinal oxygen metabolism and perfusion are accompanied by plasma protein and lipid alterations in recovered COVID-19 patients. Scientific Reports, 14(1), Article 8395. https://doi.org/10.1038/s41598-024-56834-4

Long, D., Eade, L., Sullivan, M. P., Dost, K., Meier-Menches, S. M., Goldstone, D. C., Hartinger, C. G., Wicker, J. S., & Taškova, K. (2024). AdductHunter: identifying protein-metal complex adducts in mass spectra. Journal of Cheminformatics, 16(1), Article 15. https://doi.org/10.1186/s13321-023-00797-7

Borutzki, Y., Meier-Menches, S. M., McNamara , L. E., & Anderson, J. S. (2024). Investigating biological effects of a novel organometallic complex as potential theranostic agent. Naunyn-Schmiedeberg's Archives of Pharmacology, 397(Suppl.1), S36-S36. Article P078.