Univ.-Prof. Dipl.-Ing. Dr. Jürgen Zanghellini
Jürgen Zanghellini
Summer term 2024
270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry
Winter term 2023
270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry
Summer term 2023
270103 PR Bachelor Laboratory Course B - Analytical Chemistry and Food Chemistry














Szeliova, D., Stor, J., Thiel, I., Weinguny, M., Hanscho, M., Lhota, G., Borth, N., Zanghellini, J., Ruckerbauer, D. E., & Rocha, I. (2021). Inclusion of maintenance energy improves the intracellular flux predictions of CHO. PLoS Computational Biology, 17(6), [e1009022]. https://doi.org/10.1371/journal.pcbi.1009022



Széliová, D., Ruckerbauer, D. E., Galleguillos, S. N., Petersen, L. B., Natter, K., Hanscho, M., Troyer, C., Causon, T., Schoeny, H., Christensen, H. B., Lee, D. Y., Lewis, N. E., Koellensperger, G., Hann, S., Nielsen, L. K., Borth, N., & Zanghellini, J. (2020). What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines. Metabolic engineering, 61, 288-300. https://doi.org/10.1016/j.ymben.2020.06.002

Zwirzitz, B., Wetzels, S. U., Dixon, E. D., Stessl, B., Zaiser, A., Rabanser, I., Thalguter, S., Pinior, B., Roch, F-F., Strachan, C., Zanghellini, J., Dzieciol, M., Wagner, M., & Selberherr, E. (2020). The sources and transmission routes of microbial populations throughout a meat processing facility. Npj biofilms and microbiomes, 6(1), [26]. https://doi.org/10.1038/s41522-020-0136-z


Tailored mass spectral data exploration using the specXplore interactive dashboard

Kevin Mildau (Speaker), Henry Ehlers (Contributor), Christoph Bueschl (Contributor), Justin J.J. van der Hooft (Contributor) & Jürgen Zanghellini (Contributor)

16 Nov 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Innovating Biopharmaceutical Production: Maximization of Yield and Quality with Multi-Phase Fed-Batch Processes

Jürgen Zanghellini (Keynote speaker)

25 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Designing an optimal fed-batch process using a comprehensive differential equation model

Guido Schlögel (Speaker), Mathias Gotsmy (Contributor) & Jürgen Zanghellini (Contributor)

19 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Development of a genome-scale metabolic model tailored to a CHO fed-batch process platform

Martin Hold (Speaker), Leopold Zehetner (Contributor), Manuel Dallinger (Contributor), David E. Ruckerbauer (Contributor) & Jürgen Zanghellini (Contributor)

19 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Unmasking nature's collaborators: Computing all feasible compositions of microbial communities

Marianne Mießkes (Speaker) & Jürgen Zanghellini (Contributor)

19 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Are Ribosomes Made for Maximal Growth? Insights from Resource Balance Analysis

Diana Szeliova (Speaker), Müller Stefan (Contributor) & Jürgen Zanghellini (Contributor)

24 Jul 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Sulfate limitation increases specific plasmid DNA yield in E. coli fed-batch processes

Mathias Gotsmy (Speaker), Florian Strobl (Contributor), Florian Weiß (Contributor), Petra Gruber (Contributor), Barbara Kraus (Contributor), Juergen Mairhofer (Contributor) & Jürgen Zanghellini (Contributor)

24 Jul 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Sulfate limitation increases specific plasmid DNA yield

Jürgen Zanghellini (Keynote speaker)

5 Jul 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Does ribosome composition maximize growth rate? The role of RNA instability

Diana Szeliova (Speaker), Müller Stefan (Contributor) & Jürgen Zanghellini (Contributor)

28 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Unmasking Nature's Collaborators: Computation of all feasible compositions of microbial communities

Marianne Mießkes (Speaker) & Jürgen Zanghellini (Contributor)

28 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Visualizing cross-feeding interactions in community metabolic models

Michael Predl (Speaker), Marianne Mießkes (Contributor), Jürgen Zanghellini (Contributor) & Thomas Rattei (Contributor)

28 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


specXplore: An interactive dashboard for flexible exploration of mass spectral data

Kevin Mildau (Speaker), H. Ehlers (Contributor), Christoph Bueschl (Contributor), Justin J.J. van der Hooft (Contributor) & Jürgen Zanghellini (Contributor)

1 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


specXplore: a tool for interactive and dynamic exploration of mass spectral embeddings and graphs

Kevin Mildau (Speaker), Henry Ehlers (Contributor), Christoph Bueschl (Contributor), Justin J.J. van der Hooft (Contributor) & Jürgen Zanghellini (Contributor)

30 Mar 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Carbon – Cycle Economy Demonstration (C-CED): operational concepts

Jürgen Zanghellini (Invited speaker)

14 Mar 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


An interactive workflow for single-cell multiplexed image analysis

Gabriel Braun (Speaker), Martin Schaier (Contributor), Anna Schöberl (Contributor), Sarah Theiner (Contributor), Christoph Bueschl (Contributor), Jürgen Zanghellini (Contributor) & Gunda Köllensperger (Contributor)

29 Jan 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Analyzing Optimal and Non-Optimal Resource Allocations in Whole-Cell Models

Diana Szeliova (Speaker), Müller Stefan (Contributor) & Jürgen Zanghellini (Contributor)

28 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


A human-in-the-loop workflow for single-cell multiplexed image analysis

Gabriel Braun (Keynote speaker), Martin Schaier (Contributor), Anna Schöberl (Contributor), Sarah Theiner (Contributor), Christoph Bueschl (Contributor), Jürgen Zanghellini (Contributor) & Gunda Köllensperger (Contributor)

19 Sep 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Implementation of a Genome-Scale Metabolic Model for Process Optimization of AAV-Production in HEK293 Cells

Leopold Zehetner (Speaker), Diana Szeliova (Contributor), B. Kraus (Contributor), Jürgen Zanghellini (Contributor) & Juan A. Hernandez Bort (Contributor)

13 Jun 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


If all you have is a hammer, everything looks like a nail: On the ubiquitous of elementary flux modes

Jürgen Zanghellini (Invited speaker)

23 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer

Jürgen Zanghellini (Invited speaker)

9 Dec 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


If all you have is a hammer, everything looks like a nail: On the ubiquitous of elementary flux modes

Jürgen Zanghellini (Invited speaker)

3 Dec 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification of linked metabolites allows a reliable and quantitative analysis of the finger sweat

Mathias Gotsmy (Speaker), Julia Brunmair (Contributor), Andrea Bileck (Contributor), Astrid Slany (Contributor), Samuel Matthias Meier-Menches (Contributor), Christopher Gerner (Contributor) & Jürgen Zanghellini (Contributor)

23 Sep 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


PeakBot: Machine learning based chromatographic peak picking

Christoph Bueschl (Speaker), M. Doppler (Contributor), Elisabeth Varga (Contributor) & Jürgen Zanghellini (Contributor)

7 Sep 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Beyond metabolism

Jürgen Zanghellini (Invited speaker)

26 Aug 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification of Metabolic Pairs Allow a Reliable and Quantitative Analysis of the Finger Sweat Metabolome

Mathias Gotsmy (Speaker), Samuel Matthias Meier-Menches (Contributor), Christopher Gerner (Contributor), Jürgen Zanghellini (Contributor), Julia Brunmair (Contributor), Andrea Bileck (Contributor) & Astrid Slany (Contributor)

25 Jul 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Finger Sweat Analysis Enables Metabolic Biomonitoring in Humans

Julia Brunmair (Speaker), Mathias Gotsmy (Contributor), Andrea Bileck (Contributor), Jürgen Zanghellini (Contributor), Samuel Matthias Meier-Menches (Contributor) & Christopher Gerner (Contributor)

22 Jun 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Numerical simulation of microbial processes

Jürgen Zanghellini (Invited speaker)

14 Apr 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Improving Quantitative Genome-Scale Metabolic Modeling of CHO

Diana Széliová (Speaker), David E. Ruckerbauer (Contributor), Jerneja Štor (Contributor), Dmytro Iurashev (Contributor), Harald Schöny (Contributor), Michael Hanscho (Contributor), Stephan Hann (Contributor), Gunda Köllensperger (Contributor), Isabel Rocha (Contributor), Nicole Borth (Contributor) & Jürgen Zanghellini (Contributor)

1 Mar 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Reliable Quantitative Finger Sweat Metabolome Analysis

Mathias Gotsmy (Speaker), Julia Brunmair (Contributor), Andrea Bileck (Contributor), Astrid Slany (Contributor), Samuel Matthias Meier-Menches (Contributor), Christopher Gerner (Contributor) & Jürgen Zanghellini (Contributor)

23 Feb 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Vom Nutzen und Nachteil von Netzwerken für das Leben

Jürgen Zanghellini (Invited speaker)

9 Oct 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Die Vermessung von CHO: Requirements for accurate FBA predictions

Jürgen Zanghellini (Invited speaker)

15 Jul 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Cellular robustness is not a byproduct of environmental flexibility

Jürgen Zanghellini (Speaker), Julian Julian Libiseller-Egger (Contributor), Benjamin L. Coltman (Contributor) & Matthias P. Gerstl (Contributor)

13 Jul 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Maintenance energy is essential for accurate predictions of intracellular fluxes in CHO

Diana Széliová (Speaker), David E. Ruckerbauer (Contributor), Jerneja Štor (Contributor), Isabella Thiel (Contributor), Isabel Rocha (Contributor), Nicole Borth (Contributor) & Jürgen Zanghellini (Contributor)

13 Jul 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Predictive modelling of CHO requires high precision data

Jürgen Zanghellini (Invited speaker)

3 Jul 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


Department of Analytical Chemistry

Deputy Head

Sensengasse 8
1090 Wien

T: +43-1-4277-52306

juergen.zanghellini@univie.ac.at